Planar Cell Polarity Controls Pancreatic Beta Cell Differentiation and Glucose Homeostasis
نویسندگان
چکیده
منابع مشابه
Explorer BK channels affect glucose homeostasis and cell viability of murine pancreatic beta cells
Aims/hypothesis—Evidence is accumulating that Ca2+-regulated K+ (KCa) channels are important for beta cell function. We used BK channel knockout (BK-KO) mice to examine the role of these KCa channels for glucose homeostasis, beta cell function and viability. Methods—Glucose and insulin tolerance were tested with male wild-type and BK-KO mice. BK channels were detected by single-cell RT-PCR, cyt...
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ژورنال
عنوان ژورنال: Cell Reports
سال: 2012
ISSN: 2211-1247
DOI: 10.1016/j.celrep.2012.10.016